Doxycycline is a tetracycline-class antibiotic that stops bacteria from multiplying and spreading.
Taking doxycycline within 24 to 72 hours after exposure allows the medicine to act before an infection becomes established.

DoxyPEP is suitable for people at ongoing risk of bacterial STIs — for example, those with multiple partners or whose partners have recently tested positive.
You’ll complete a short online clinical assessment to confirm your suitability, medical history, and allergies before any prescription is issued.

When prescribed correctly and taken as directed, doxycycline is considered safe for most adults.
Common side effects include:
• Mild nausea or upset stomach
• Increased sun sensitivity
• Diarrhoea or thrush
Serious side effects are rare, but stop taking the medicine and contact a clinician if you experience rash, swelling, or yellowing of the skin/eyes.

According to BASHH guidance:
• Take 200 mg (2 tablets) as soon as possible after unprotected sex — ideally within 24 to 72 hours.
• Then take 100 mg (1 tablet daily) for 3 days.
Always follow the pharmacy label and complete the course.

No — Doxycycline only helps prevent certain bacterial infections such as chlamydia and syphilis.
It does not protect against HIV, gonorrhoea, or viral STIs.
You should continue to use condoms and attend routine STI screening for full protection.

1. Complete a secure online consultation form.
2. A UK-registered clinician reviews your answers.
3. If suitable, a private prescription is issued and dispensed by a GPhC-registered pharmacy.
4. Your medicine is posted discreetly:
• Same-day delivery in London (orders before 11 am)
• Next-day delivery UK-wide (orders before 5 pm)

We offer flexible pricing options to suit different needs:

Single Purchase
£59.99 for 25 treatments
One-off purchase including clinical review, private prescription, and tracked delivery

Monthly Subscription
£44.50 per month for 25 treatments
Minimum 6-month commitment; includes clinical review, repeat prescription, and delivery each month

Annual Plan (Pre-paid)
£530 per year (25 treatments/month)
Pay annually and save; includes 12 months of medication, prescriptions, and delivery

All options include a clinician review, private prescription, and discreet tracked delivery. No hidden fees.

Some patients use DoxyPEP as part of an ongoing sexual-health prevention plan.
Your prescriber will review your use regularly to ensure it remains appropriate and safe.

Stop taking doxycycline and contact us or your GP immediately if you experience:
• Severe rash or swelling
• Difficulty breathing
• Yellowing of skin or eyes
For urgent issues, call 111 or 999

Contact our clinical team here for confidential advice.